CDC6 Mouse Monoclonal Antibody [Clone ID: LBI7B12]
Product Specifications
Background
The protein encoded by this gene is highly similar to Saccharomyces cerevisiae Cdc6, a protein essential for the initiation of DNA replication. This protein functions as a regulator at the early steps of DNA replication. It localizes in cell nucleus during cell cyle G1, but translocates to the cytoplasm at the start of S phase. The subcellular translocation of this protein during cell cyle is regulated through its phosphorylation by Cdks. Transcription of this protein was reported to be regulated in response to mitogenic signals through transcriptional control mechanism involving E2F proteins. [provided by RefSeq, Jul 2008]
Synonyms
CDC18L; HsCDC6; HsCDC18
Gene Name
Cell division cycle 6
Gene ID
990
UniProt
Q99741
Conjugation
Unconjugated
Related Pathways
Cell cycle
Field of Research
Cell cycle
Concentration
1 mg/ml
Dilution
WB 1:2000, IHC 1:150
Form
PBS (PH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide.
Buffer
PBS (PH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide.
Storage Conditions
Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.
Symbol
CDC6
Overview
CDC6 mouse monoclonal antibody, clone LBI7B12
Gene ID URL
https://www.ncbi.nlm.nih.gov/gene/?term=990
Uniprot URL
https://www.uniprot.org/uniprot/Q99741
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