Prostate Specific Antigen (KLK3) Mouse Monoclonal Antibody [Clone ID: LBI2C9]
Product Specifications
Background
Kallikreins are a subgroup of serine proteases having diverse physiological functions. Growing evidence suggests that many kallikreins are implicated in carcinogenesis and some have potential as novel cancer and other disease biomarkers. This gene is one of the fifteen kallikrein subfamily members located in a cluster on chromosome 19. Its protein product is a protease present in seminal plasma. It is thought to function normally in the liquefaction of seminal coagulum, presumably by hydrolysis of the high molecular mass seminal vesicle protein. Serum level of this protein, called PSA in the clinical setting, is useful in the diagnosis and monitoring of prostatic carcinoma. Alternate splicing of this gene generates several transcript variants encoding different isoforms. [provided by RefSeq, Jul 2008]
Synonyms
APS; hK3; KLK2A1; PSA
Gene Name
Kallikrein related peptidase 3
Gene ID
354
UniProt
P07288
Conjugation
Unconjugated
Related Pathways
Pathways in cancer, Prostate cancer
Field of Research
Pathways in cancer, Prostate cancer
Concentration
1 mg/ml
Dilution
WB 1:2000, IHC 1:150
Form
PBS (PH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide.
Buffer
PBS (PH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide.
Function
Druggable Genome, Protease, Secreted Protein
Storage Conditions
Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.
Symbol
KLK3
Overview
KLK3 mouse monoclonal antibody, clone LBI2C9
Gene ID URL
https://www.ncbi.nlm.nih.gov/gene/?term=354
Uniprot URL
https://www.uniprot.org/uniprot/P07288
Curated Selection
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