IKBKE Mouse Monoclonal Antibody [Clone ID: LBI1E4]
Product Specifications
Background
IKBKE is a noncanonical I-kappa-B (see MIM 164008) kinase (IKK) that is essential for regulating antiviral signaling pathways. IKBKE has also been identified as a breast cancer (MIM 114480) oncogene and is amplified and overexpressed in over 30% of breast carcinomas and breast cancer cell lines (Hutti et al., 2009 [PubMed 19481526]) . [supplied by OMIM, Oct 2009]
Overview
IKBKE mouse monoclonal antibody, clone LBI1E4
Synonyms
IKK-E; IKK-i; IKKE; IKKI
Gene Name
Inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase epsilon
Gene ID
9641
UniProt
Q14164
Conjugation
Unconjugated
Related Pathways
Cytosolic DNA-sensing pathway, RIG-I-like receptor signaling pathway, Toll-like receptor signaling pathway
Field of Research
Cytosolic DNA-sensing pathway, RIG-I-like receptor signaling pathway, Toll-like receptor signaling pathway
Concentration
1 mg/ml
Dilution
WB 1:500, IHC 1:150
Form
PBS (PH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide.
Buffer
PBS (PH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide.
Function
Druggable Genome, Protein Kinase
Storage Conditions
Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.
Symbol
IKBKE
Gene ID URL
https://www.ncbi.nlm.nih.gov/gene/?term=9641
Uniprot URL
https://www.uniprot.org/uniprot/Q14164
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