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IKBKE Mouse Monoclonal Antibody [Clone ID: LBI1E4]

Product Specifications

Background

IKBKE is a noncanonical I-kappa-B (see MIM 164008) kinase (IKK) that is essential for regulating antiviral signaling pathways. IKBKE has also been identified as a breast cancer (MIM 114480) oncogene and is amplified and overexpressed in over 30% of breast carcinomas and breast cancer cell lines (Hutti et al., 2009 [PubMed 19481526]) . [supplied by OMIM, Oct 2009]

Overview

IKBKE mouse monoclonal antibody, clone LBI1E4

Synonyms

IKK-E; IKK-i; IKKE; IKKI

Gene Name

Inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase epsilon

Gene ID

9641

UniProt

Q14164

Conjugation

Unconjugated

Related Pathways

Cytosolic DNA-sensing pathway, RIG-I-like receptor signaling pathway, Toll-like receptor signaling pathway

Field of Research

Cytosolic DNA-sensing pathway, RIG-I-like receptor signaling pathway, Toll-like receptor signaling pathway

Concentration

1 mg/ml

Dilution

WB 1:500, IHC 1:150

Form

PBS (PH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide.

Buffer

PBS (PH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide.

Function

Druggable Genome, Protein Kinase

Storage Conditions

Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.

Symbol

IKBKE

Gene ID URL

https://www.ncbi.nlm.nih.gov/gene/?term=9641

Uniprot URL

https://www.uniprot.org/uniprot/Q14164

Frequently Asked Questions

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