CYP7B1 Mouse Monoclonal Antibody [Clone ID: LBI1G7]

Product Specifications

Background

This gene encodes a member of the cytochrome P450 superfamily of enzymes. The cytochrome P450 proteins are monooxygenases which catalyze many reactions involved in drug metabolism and synthesis of cholesterol, steroids and other lipids. This endoplasmic reticulum membrane protein catalyzes the first reaction in the cholesterol catabolic pathway of extrahepatic tissues, which converts cholesterol to bile acids. This enzyme likely plays a minor role in total bile acid synthesis, but may also be involved in the development of atherosclerosis, neurosteroid metabolism and sex hormone synthesis. [provided by RefSeq, Jul 2008]

Overview

CYP7B1 mouse monoclonal antibody, clone LBI1G7

Synonyms

CBAS3; CP7B; SPG5A

Gene Name

Cytochrome P450 family 7 subfamily B member 1

Gene ID

9420

UniProt

O75881

Conjugation

Unconjugated

Related Pathways

Primary bile acid biosynthesis

Field of Research

Primary bile acid biosynthesis

Concentration

1 mg/ml

Dilution

WB 1:500, IHC 1:500

Form

PBS (PH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide.

Buffer

PBS (PH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide.

Function

Druggable Genome, P450, Transmembrane

Storage Conditions

Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.