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PON3 Mouse Monoclonal Antibody [Clone ID: LBI1B12]

Product Specifications

Background

This gene is a member of the paraoxonase family and lies in a cluster on chromosome 7 with the other two family members. The encoded protein is secreted into the bloodstream and associates with high-density lipoprotein (HDL) . The protein also rapidly hydrolyzes lactones and can inhibit the oxidation of low-density lipoprotein (LDL), a function that is believed to slow the initiation and progression of atherosclerosis. Alternatively spliced variants which encode different protein isoforms have been described; however, only one has been fully characterized. [provided by RefSeq, Jul 2008]

Synonyms

Lactonase 3; paraoxanase-3; paraoxonase 3; serum paraoxonase

Gene Name

Paraoxonase 3

Gene ID

5446

UniProt

Q15166

Conjugation

Unconjugated

Related Pathways

Metabolic pathways

Field of Research

Metabolic pathways

Concentration

1 mg/ml

Dilution

WB 1:2000, IHC 1:150

Form

PBS (PH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide.

Buffer

PBS (PH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide.

Function

Secreted Protein, Transmembrane

Storage Conditions

Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.

Symbol

PON3

Overview

PON3 mouse monoclonal antibody, clone LBI1B12

Gene ID URL

https://www.ncbi.nlm.nih.gov/gene/?term=5446

Uniprot URL

https://www.uniprot.org/uniprot/Q15166

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