C Fos (FOS) Mouse Monoclonal Antibody [Clone ID: LBI1F12]
Product Specifications
Background
The Fos gene family consists of 4 members: FOS, FOSB, FOSL1, and FOSL2. These genes encode leucine zipper proteins that can dimerize with proteins of the JUN family, thereby forming the transcription factor complex AP-1. As such, the FOS proteins have been implicated as regulators of cell proliferation, differentiation, and transformation. In some cases, expression of the FOS gene has also been associated with apoptotic cell death. [provided by RefSeq, Jul 2008]
Synonyms
AP-1; C-FOS; p55
Gene Name
Fos proto-oncogene, AP-1 transcription factor subunit
Gene ID
2353
UniProt
P01100
Conjugation
Unconjugated
Related Pathways
B cell receptor signaling pathway, Colorectal cancer, MAPK signaling pathway, Pathways in cancer, T cell receptor signaling pathway, Toll-like receptor signaling pathway
Field of Research
B cell receptor signaling pathway, Colorectal cancer, MAPK signaling pathway, Pathways in cancer, T cell receptor signaling pathway, Toll-like receptor signaling pathway
Concentration
1 mg/ml
Dilution
WB 1:2000, IHC 1:150
Form
PBS (PH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide.
Buffer
PBS (PH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide.
Function
Druggable Genome, Transcription Factors
Storage Conditions
Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.
Symbol
FOS
Overview
FOS mouse monoclonal antibody, clone LBI1F12
Gene ID URL
https://www.ncbi.nlm.nih.gov/gene/?term=2353
Uniprot URL
https://www.uniprot.org/uniprot/P01100
Curated Selection
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