Dishevelled 2 (DVL2) Mouse Monoclonal Antibody [Clone ID: LBI2E11]
Product Specifications
Background
This gene encodes a member of the dishevelled (dsh) protein family. The vertebrate dsh proteins have approximately 40% amino acid sequence similarity with Drosophila dsh. This gene encodes a 90-kD protein that undergoes posttranslational phosphorylation to form a 95-kD cytoplasmic protein, which may play a role in the signal transduction pathway mediated by multiple Wnt proteins. The mechanisms of dishevelled function in Wnt signaling are likely to be conserved among metazoans. [provided by RefSeq, Jul 2008]
Overview
DVL2 mouse monoclonal antibody, clone LBI2E11
Synonyms
Dishevelled; dishevelled 2; dishevelled 2 (homologous to Drosophila dsh) ; DSH homolog 2; dsh homolog 2 (Drosophila) ; segment polarity protein dishevelled homolog DVL-2
Gene Name
Dishevelled segment polarity protein 2
Gene ID
1856
UniProt
O14641
Conjugation
Unconjugated
Related Pathways
Basal cell carcinoma, Colorectal cancer, Melanogenesis, Notch signaling pathway, Pathways in cancer, Wnt signaling pathway
Field of Research
Basal cell carcinoma, Colorectal cancer, Melanogenesis, Notch signaling pathway, Pathways in cancer, Wnt signaling pathway
Concentration
1 mg/ml
Dilution
WB 1:2000, IHC 1:150
Form
PBS (PH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide.
Buffer
PBS (PH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide.
Function
Druggable Genome, ES Cell Differentiation/IPS
Storage Conditions
Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.
Symbol
DVL2
Gene ID URL
https://www.ncbi.nlm.nih.gov/gene/?term=1856
Uniprot URL
https://www.uniprot.org/uniprot/O14641
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