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C Fos (FOS) Mouse Monoclonal Antibody [Clone ID: LBI3B8]

Product Specifications

Background

The Fos gene family consists of 4 members: FOS, FOSB, FOSL1, and FOSL2. These genes encode leucine zipper proteins that can dimerize with proteins of the JUN family, thereby forming the transcription factor complex AP-1. As such, the FOS proteins have been implicated as regulators of cell proliferation, differentiation, and transformation. In some cases, expression of the FOS gene has also been associated with apoptotic cell death. [provided by RefSeq, Jul 2008]

Overview

FOS mouse monoclonal antibody, clone LBI3B8

Synonyms

AP-1; C-FOS; p55

Gene Name

Fos proto-oncogene, AP-1 transcription factor subunit

Gene ID

2353

UniProt

P01100

Conjugation

Unconjugated

Related Pathways

B cell receptor signaling pathway, Colorectal cancer, MAPK signaling pathway, Pathways in cancer, T cell receptor signaling pathway, Toll-like receptor signaling pathway

Field of Research

B cell receptor signaling pathway, Colorectal cancer, MAPK signaling pathway, Pathways in cancer, T cell receptor signaling pathway, Toll-like receptor signaling pathway

Concentration

1 mg/ml

Dilution

WB 1:2000, IHC 1:150

Form

PBS (PH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide.

Buffer

PBS (PH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide.

Function

Druggable Genome, Transcription Factors

Storage Conditions

Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.

Symbol

FOS

Gene ID URL

https://www.ncbi.nlm.nih.gov/gene/?term=2353

Uniprot URL

https://www.uniprot.org/uniprot/P01100

Frequently Asked Questions

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