VEGF Receptor 1 (FLT1) Mouse Monoclonal Antibody [Clone ID: LBI8G6]
Product Specifications
Background
This gene encodes a member of the vascular endothelial growth factor receptor (VEGFR) family. VEGFR family members are receptor tyrosine kinases (RTKs) which contain an extracellular ligand-binding region with seven immunoglobulin (Ig) -like domains, a transmembrane segment, and a tyrosine kinase (TK) domain within the cytoplasmic domain. This protein binds to VEGFR-A, VEGFR-B and placental growth factor and plays an important role in angiogenesis and vasculogenesis. Expression of this receptor is found in vascular endothelial cells, placental trophoblast cells and peripheral blood monocytes. Multiple transcript variants encoding different isoforms have been found for this gene. Isoforms include a full-length transmembrane receptor isoform and shortened, soluble isoforms. The soluble isoforms are associated with the onset of pre-eclampsia. [provided by RefSeq, May 2009]
Synonyms
FLT; FLT-1; VEGFR-1; VEGFR1
Gene Name
Fms related tyrosine kinase 1
Gene ID
2321
UniProt
P17948
Conjugation
Unconjugated
Related Pathways
Cytokine-cytokine receptor interaction, Endocytosis, Focal adhesion
Field of Research
Cytokine-cytokine receptor interaction, Endocytosis, Focal adhesion
Concentration
1 mg/ml
Dilution
WB 1:2000
Form
PBS (PH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide.
Buffer
PBS (PH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide.
Function
Druggable Genome, Protein Kinase, Secreted Protein
Storage Conditions
Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.
Symbol
FLT1
Overview
FLT1 mouse monoclonal antibody, clone LBI8G6
Gene ID URL
https://www.ncbi.nlm.nih.gov/gene/?term=2321
Uniprot URL
https://www.uniprot.org/uniprot/P17948
Curated Selection
Explore Other Products
Discover premium biology products from our extensive collection of 20M+ items
