Osteopontin (SPP1) Mouse Monoclonal Antibody [Clone ID: LBI2F2]

Product Specifications

Background

The protein encoded by this gene is involved in the attachment of osteoclasts to the mineralized bone matrix. The encoded protein is secreted and binds hydroxyapatite with high affinity. The osteoclast vitronectin receptor is found in the cell membrane and may be involved in the binding to this protein. This protein is also a cytokine that upregulates expression of interferon-gamma and interleukin-12. Several transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Oct 2011]

Overview

SPP1 mouse monoclonal antibody, clone LBI2F2

Synonyms

BNSP; BSPI; ETA-1; OPN

Gene Name

Secreted phosphoprotein 1

Gene ID

6696

UniProt

P10451

Conjugation

Unconjugated

Related Pathways

ECM-receptor interaction, Focal adhesion, Toll-like receptor signaling pathway

Field of Research

ECM-receptor interaction, Focal adhesion, Toll-like receptor signaling pathway

Concentration

1 mg/ml

Dilution

WB 1:2000, IHC 1:150

Form

PBS (PH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide.

Buffer

PBS (PH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide.

Function

Druggable Genome, Secreted Protein

Storage Conditions

Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.