TNFRSF18 Mouse Monoclonal Antibody [Clone ID: LBI1A3]
Product Specifications
Background
This gene encodes a member of the TNF-receptor superfamily. The encoded receptor has been shown to have increased expression upon T-cell activation, and it is thought to play a key role in dominant immunological self-tolerance maintained by CD25 (+) CD4 (+) regulatory T cells. Knockout studies in mice also suggest the role of this receptor is in the regulation of CD3-driven T-cell activation and programmed cell death. Three alternatively spliced transcript variants of this gene encoding distinct isoforms have been reported. [provided by RefSeq, Feb
Synonyms
AITR; CD357; GITR; GITR-D
Gene Name
Tumor necrosis factor receptor superfamily member 18
Gene ID
8784
UniProt
Q9Y5U5
Conjugation
Unconjugated
Related Pathways
Cytokine-cytokine receptor interaction
Field of Research
Cytokine-cytokine receptor interaction
Concentration
1 mg/ml
Dilution
WB 1:2000
Form
PBS (PH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide.
Buffer
PBS (PH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide.
Function
Druggable Genome, Secreted Protein, Transmembrane
Storage Conditions
Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.
Symbol
TNFRSF18
Overview
TNFRSF18 mouse monoclonal antibody, clone LBI1A3
Gene ID URL
https://www.ncbi.nlm.nih.gov/gene/?term=8784
Uniprot URL
https://www.uniprot.org/uniprot/Q9Y5U5
Curated Selection
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