HDAC4 Mouse Monoclonal Antibody [Clone ID: LBI1A12]
Product Specifications
Background
Histones play a critical role in transcriptional regulation, cell cycle progression, and developmental events. Histone acetylation/deacetylation alters chromosome structure and affects transcription factor access to DNA. The protein encoded by this gene belongs to class II of the histone deacetylase/acuc/apha family. It possesses histone deacetylase activity and represses transcription when tethered to a promoter. This protein does not bind DNA directly, but through transcription factors MEF2C and MEF2D. It seems to interact in a multiprotein complex with RbAp48 and HDAC3. [provided by RefSeq, Jul 2008]
Synonyms
AHO3; BDMR; HA6116; HD4; HDAC-4; HDAC-A; HDACA
Gene Name
Histone deacetylase 4
Gene ID
9759
UniProt
P56524
Conjugation
Unconjugated
Concentration
1 mg/ml
Dilution
WB 1:2000
Form
PBS (PH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide.
Buffer
PBS (PH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide.
Function
Druggable Genome, Transcription Factors
Storage Conditions
Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.
Symbol
HDAC4
Overview
HDAC4 mouse monoclonal antibody, clone LBI1A12
Gene ID URL
https://www.ncbi.nlm.nih.gov/gene/?term=9759
Uniprot URL
https://www.uniprot.org/uniprot/P56524
Curated Selection
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