MMP7 Mouse Monoclonal Antibody [Clone ID: LBI3E9]
Product Specifications
Background
Proteins of the matrix metalloproteinase (MMP) family are involved in the breakdown of extracellular matrix in normal physiological processes, such as embryonic development, reproduction, and tissue remodeling, as well as in disease processes, such as arthritis and metastasis. Most MMP's are secreted as inactive proproteins which are activated when cleaved by extracellular proteinases. The enzyme encoded by this gene degrades proteoglycans, fibronectin, elastin and casein and differs from most MMP family members in that it lacks a conserved C-terminal protein domain. The enzyme is involved in wound healing, and studies in mice suggest that it regulates the activity of defensins in intestinal mucosa. The gene is part of a cluster of MMP genes which localize to chromosome 11q22.3. [provided by RefSeq, Jul 2008]
Synonyms
MMP-7; MPSL1; PUMP-1
Gene Name
Matrix metallopeptidase 7
Gene ID
4316
UniProt
P09237
Conjugation
Unconjugated
Related Pathways
Wnt signaling pathway
Field of Research
Wnt signaling pathway
Concentration
1 mg/ml
Dilution
WB 1:2000, IHC 1:150
Form
PBS (PH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide.
Buffer
PBS (PH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide.
Function
Druggable Genome, Protease
Storage Conditions
Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.
Symbol
MMP7
Overview
MMP7 mouse monoclonal antibody, clone LBI3E9
Gene ID URL
https://www.ncbi.nlm.nih.gov/gene/?term=4316
Uniprot URL
https://www.uniprot.org/uniprot/P09237
Curated Selection
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