PTCH2 Mouse Monoclonal Antibody [Clone ID: LBI1F5]

Product Specifications

Background

This gene encodes a transmembrane receptor of the patched gene family. The encoded protein may function as a tumor suppressor in the hedgehog signaling pathway. Alterations in this gene have been associated with nevoid basal cell carcinoma syndrome, basal cell carcinoma, medulloblastoma, and susceptibility to congenital macrostomia. Alternatively spliced transcript variants have been described. [provided by RefSeq, Oct 2009]

Overview

PTCH2 mouse monoclonal antibody, clone LBI1F5

Synonyms

PTC2

Gene Name

Patched 2

Gene ID

8643

UniProt

Q9Y6C5

Conjugation

Unconjugated

Related Pathways

Basal cell carcinoma, Hedgehog signaling pathway, Pathways in cancer

Field of Research

Basal cell carcinoma, Hedgehog signaling pathway, Pathways in cancer

Concentration

1 mg/ml

Dilution

WB 1:2000

Form

PBS (PH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide.

Buffer

PBS (PH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide.

Function

Druggable Genome, ES Cell Differentiation/IPS, Transmembrane

Storage Conditions

Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.