XRCC3 Mouse Monoclonal Antibody [Clone ID: LBI4F3]

Product Specifications

Background

This gene encodes a member of the RecA/Rad51-related protein family that participates in homologous recombination to maintain chromosome stability and repair DNA damage. This gene functionally complements Chinese hamster irs1SF, a repair-deficient mutant that exhibits hypersensitivity to a number of different DNA-damaging agents and is chromosomally unstable. A rare microsatellite polymorphism in this gene is associated with cancer in patients of varying radiosensitivity. Alternatively spliced transcript variants encoding the same protein have been identified. [provided by RefSeq, Jul 2008]

Overview

XRCC3 mouse monoclonal antibody, clone LBI4F3

Synonyms

CMM6

Gene Name

X-ray repair complementing defective repair in Chinese hamster cells 3

Gene ID

7517

UniProt

O43542

Conjugation

Unconjugated

Related Pathways

Homologous recombination

Field of Research

Homologous recombination

Concentration

1 mg/ml

Dilution

WB 1:2000

Form

PBS (PH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide.

Buffer

PBS (PH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide.

Function

Druggable Genome

Storage Conditions

Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.