XRCC3 Mouse Monoclonal Antibody [Clone ID: LBI4C8]
Product Specifications
Background
This gene encodes a member of the RecA/Rad51-related protein family that participates in homologous recombination to maintain chromosome stability and repair DNA damage. This gene functionally complements Chinese hamster irs1SF, a repair-deficient mutant that exhibits hypersensitivity to a number of different DNA-damaging agents and is chromosomally unstable. A rare microsatellite polymorphism in this gene is associated with cancer in patients of varying radiosensitivity. Alternatively spliced transcript variants encoding the same protein have been identified. [provided by RefSeq, Jul 2008]
Synonyms
CMM6
Gene Name
X-ray repair complementing defective repair in Chinese hamster cells 3
Gene ID
7517
UniProt
O43542
Conjugation
Unconjugated
Related Pathways
Homologous recombination
Field of Research
Homologous recombination
Concentration
1 mg/ml
Dilution
WB 1:2000
Form
PBS (PH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide.
Buffer
PBS (PH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide.
Function
Druggable Genome
Storage Conditions
Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.
Symbol
XRCC3
Overview
XRCC3 mouse monoclonal antibody, clone LBI4C8
Gene ID URL
https://www.ncbi.nlm.nih.gov/gene/?term=7517
Uniprot URL
https://www.uniprot.org/uniprot/O43542
Curated Selection
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