FLIP (CFLAR) Mouse Monoclonal Antibody [Clone ID: LBI2H3]
Product Specifications
Background
The protein encoded by this gene is a regulator of apoptosis and is structurally similar to caspase-8. However, the encoded protein lacks caspase activity and appears to be itself cleaved into two peptides by caspase-8. Several transcript variants encoding different isoforms have been found for this gene, and partial evidence for several more variants exists. [provided by RefSeq, Feb 2011]
Overview
CFLAR mouse monoclonal antibody, clone LBI2H3
Synonyms
CASH; CASP8AP1; CLARP; Casper; FLAME; FLAME-1; FLAME1; FLIP; I-FLICE; MRIT; c-FLIP; c-FLIPL; c-FLIPR; c-FLIPS
Gene Name
CASP8 and FADD like apoptosis regulator
Gene ID
8837
UniProt
O15519
Conjugation
Unconjugated
Related Pathways
Apoptosis
Field of Research
Apoptosis
Concentration
1 mg/ml
Dilution
WB 1:500
Form
PBS (PH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide.
Buffer
PBS (PH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide.
Function
Druggable Genome, Protease
Storage Conditions
Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.
Symbol
CFLAR
Gene ID URL
https://www.ncbi.nlm.nih.gov/gene/?term=8837
Uniprot URL
https://www.uniprot.org/uniprot/O15519
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