IKZF3 Mouse Monoclonal Antibody [Clone ID: LBI7E11]
Product Specifications
Background
This gene encodes a member of the Ikaros family of zinc-finger proteins. Three members of this protein family (Ikaros, Aiolos and Helios) are hematopoietic-specific transcription factors involved in the regulation of lymphocyte development. This gene product is a transcription factor that is important in the regulation of B lymphocyte proliferation and differentiation. Both Ikaros and Aiolos can participate in chromatin remodeling. Regulation of gene expression in B lymphocytes by Aiolos is complex as it appears to require the sequential formation of Ikaros homodimers, Ikaros/Aiolos heterodimers, and Aiolos homodimers. Several alternative transcripts encoding different isoforms have been described, as well as some non-protein coding variants. [provided by RefSeq, Apr 2012]
Synonyms
AIO; AIOLOS; ZNFN1A3
Gene Name
IKAROS family zinc finger 3
Gene ID
22806
UniProt
Q9UKT9
Conjugation
Unconjugated
Concentration
1 mg/ml
Dilution
WB 1:2000, IHC 1:150
Form
PBS (PH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide.
Buffer
PBS (PH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide.
Storage Conditions
Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.
Symbol
IKZF3
Overview
IKZF3 mouse monoclonal antibody, clone LBI7E11
Gene ID URL
https://www.ncbi.nlm.nih.gov/gene/?term=22806
Uniprot URL
https://www.uniprot.org/uniprot/Q9UKT9
Curated Selection
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