SETD2 Mouse Monoclonal Antibody [Clone ID: LBI1E1]
Product Specifications
Background
Huntington's disease (HD), a neurodegenerative disorder characterized by loss of striatal neurons, is caused by an expansion of a polyglutamine tract in the HD protein huntingtin. This gene encodes a protein belonging to a class of huntingtin interacting proteins characterized by WW motifs. This protein is a histone methyltransferase that is specific for lysine-36 of histone H3, and methylation of this residue is associated with active chromatin. This protein also contains a novel transcriptional activation domain and has been found associated with hyperphosphorylated RNA polymerase II. [provided by RefSeq, Aug
Synonyms
HBP231; HIF-1; HIP-1; HSPC069; HYPB; KMT3A; LLS; p231HBP; SET2
Gene Name
SET domain containing 2
Gene ID
29072
UniProt
Q9BYW2
Conjugation
Unconjugated
Related Pathways
Lysine degradation
Field of Research
Lysine degradation
Concentration
1 mg/ml
Dilution
WB 1:2000, IHC 1:150
Form
PBS (PH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide.
Buffer
PBS (PH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide.
Function
Druggable Genome
Storage Conditions
Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.
Symbol
SETD2
Overview
SETD2 mouse monoclonal antibody, clone LBI1E1
Gene ID URL
https://www.ncbi.nlm.nih.gov/gene/?term=29072
Uniprot URL
https://www.uniprot.org/uniprot/Q9BYW2
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