PAFAH1B3 Mouse Monoclonal Antibody [Clone ID: LBI2A5]

Product Specifications

Background

This gene encodes an acetylhydrolase that catalyzes the removal of an acetyl group from the glycerol backbone of platelet-activating factor. The encoded enzyme is a subunit of the platelet-activating factor acetylhydrolase isoform 1B complex, which consists of the catalytic beta and gamma subunits and the regulatory alpha subunit. This complex functions in brain development. A translocation between this gene on chromosome 19 and the CDC-like kinase 2 gene on chromosome 1 has been observed, and was associated with mental retardation, ataxia, and atrophy of the brain. Alternatively spliced transcript variants have been described. [provided by RefSeq, Mar 2009]

Overview

Purified PAFAH1B3 mouse monoclonal antibody, clone LBI2A5

Synonyms

PAFAHG

Gene Name

Platelet activating factor acetylhydrolase 1b catalytic subunit 3

Gene ID

5050

UniProt

Q15102

Conjugation

Unconjugated

Related Pathways

Ether lipid metabolism, Metabolic pathways

Field of Research

Ether lipid metabolism, Metabolic pathways

Concentration

1 mg/ml

Dilution

WB 1:2000

Form

PBS (PH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide.

Buffer

PBS (PH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide.

Function

Druggable Genome

Storage Conditions

Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.