PAFAH1B3 Mouse Monoclonal Antibody [Clone ID: LBI2A5]
Product Specifications
Background
This gene encodes an acetylhydrolase that catalyzes the removal of an acetyl group from the glycerol backbone of platelet-activating factor. The encoded enzyme is a subunit of the platelet-activating factor acetylhydrolase isoform 1B complex, which consists of the catalytic beta and gamma subunits and the regulatory alpha subunit. This complex functions in brain development. A translocation between this gene on chromosome 19 and the CDC-like kinase 2 gene on chromosome 1 has been observed, and was associated with mental retardation, ataxia, and atrophy of the brain. Alternatively spliced transcript variants have been described. [provided by RefSeq, Mar 2009]
Synonyms
PAFAHG
Gene Name
Platelet activating factor acetylhydrolase 1b catalytic subunit 3
Gene ID
5050
UniProt
Q15102
Conjugation
Unconjugated
Related Pathways
Ether lipid metabolism, Metabolic pathways
Field of Research
Ether lipid metabolism, Metabolic pathways
Concentration
1 mg/ml
Dilution
WB 1:2000
Form
PBS (PH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide.
Buffer
PBS (PH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide.
Function
Druggable Genome
Storage Conditions
Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.
Symbol
PAFAH1B3
Overview
Purified PAFAH1B3 mouse monoclonal antibody, clone LBI2A5
Gene ID URL
https://www.ncbi.nlm.nih.gov/gene/?term=5050
Uniprot URL
https://www.uniprot.org/uniprot/Q15102
Curated Selection
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