CD30 (TNFRSF8) Mouse Monoclonal Antibody [Clone ID: LBI3A2]
Product Specifications
Background
The protein encoded by this gene is a member of the TNF-receptor superfamily. This receptor is expressed by activated, but not by resting, T and B cells. TRAF2 and TRAF5 can interact with this receptor, and mediate the signal transduction that leads to the activation of NF-kappaB. This receptor is a positive regulator of apoptosis, and also has been shown to limit the proliferative potential of autoreactive CD8 effector T cells and protect the body against autoimmunity. Two alternatively spliced transcript variants of this gene encoding distinct isoforms have been reported. [provided by RefSeq, Jul 2008]
Overview
TNFRSF8 mouse monoclonal antibody, clone LBI3A2
Synonyms
CD30; D1S166E; Ki-1
Gene Name
Tumor necrosis factor receptor superfamily member 8
Gene ID
943
UniProt
P28908
Conjugation
Unconjugated
Related Pathways
Cytokine-cytokine receptor interaction
Field of Research
Cytokine-cytokine receptor interaction
Concentration
1 mg/ml
Dilution
WB 1:500, IHC 1:150, FLOW 1:100
Form
PBS (PH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide.
Buffer
PBS (PH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide.
Function
Druggable Genome, ES Cell Differentiation/IPS, Stem cell - Pluripotency, Transmembrane
Storage Conditions
Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.
Symbol
TNFRSF8
Gene ID URL
https://www.ncbi.nlm.nih.gov/gene/?term=943
Uniprot URL
https://www.uniprot.org/uniprot/P28908
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