UBE2B Mouse Monoclonal Antibody [Clone ID: LBI1E11]

Product Specifications

Background

The modification of proteins with ubiquitin is an important cellular mechanism for targeting abnormal or short-lived proteins for degradation. Ubiquitination involves at least three classes of enzymes: ubiquitin-activating enzymes, or E1s, ubiquitin-conjugating enzymes, or E2s, and ubiquitin-protein ligases, or E3s. This gene encodes a member of the E2 ubiquitin-conjugating enzyme family. This enzyme is required for post-replicative DNA damage repair. Its protein sequence is 100% identical to the mouse, rat, and rabbit homologs, which indicates that this enzyme is highly conserved in eukaryotic evolution. [provided by RefSeq, Jul 2008]

Overview

UBE2B mouse monoclonal antibody, clone LBI1E11

Synonyms

E2-17kDa; HHR6B; HR6B; RAD6B; UBC2

Gene Name

Ubiquitin conjugating enzyme E2 B

Gene ID

7320

UniProt

P63146

Conjugation

Unconjugated

Related Pathways

Ubiquitin mediated proteolysis

Field of Research

Ubiquitin mediated proteolysis

Concentration

1 mg/ml

Dilution

WB 1:2000

Form

PBS (PH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide.

Buffer

PBS (PH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide.

Function

Druggable Genome

Storage Conditions

Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.