ITGB3BP Mouse Monoclonal Antibody [Clone ID: LBI4H1]
Product Specifications
Background
This gene encodes a transcriptional coregulator that binds to and enhances the activity of members of the nuclear receptor families, thyroid hormone receptors and retinoid X receptors. This protein also acts as a corepressor of NF-kappaB-dependent signaling. This protein induces apoptosis in breast cancer cells through a caspase 2-mediated signaling pathway. This protein is also a component of the centromere-specific histone H3 variant nucleosome associated complex (CENP-NAC) and may be involved in mitotic progression by recruiting the histone H3 variant CENP-A to the centromere. Alternate splicing results in multiple transcript variants. [provided by RefSeq, Sep 2011]
Synonyms
CENP-R; CENPR; HSU37139; NRIF3; TAP20
Gene Name
Integrin subunit beta 3 binding protein
Gene ID
23421
UniProt
Q13352
Conjugation
Unconjugated
Concentration
1 mg/ml
Dilution
WB 1:2000
Form
PBS (PH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide.
Buffer
PBS (PH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide.
Function
Druggable Genome, Stem cell - Pluripotency, Transcription Factors
Storage Conditions
Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.
Symbol
ITGB3BP
Overview
ITGB3BP mouse monoclonal antibody, clone LBI4H1
Gene ID URL
https://www.ncbi.nlm.nih.gov/gene/?term=23421
Uniprot URL
https://www.uniprot.org/uniprot/Q13352
Curated Selection
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