GBA Mouse Monoclonal Antibody [Clone ID: LBI4G4]

Product Specifications

Background

This gene encodes a lysosomal membrane protein that cleaves the beta-glucosidic linkage of glycosylceramide, an intermediate in glycolipid metabolism. Mutations in this gene cause Gaucher disease, a lysosomal storage disease characterized by an accumulation of glucocerebrosides. A related pseudogene is approximately 12 kb downstream of this gene on chromosome 1. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jan 2010]

Overview

GBA mouse monoclonal antibody, clone LBI4G4

Synonyms

GBA1; GCB; GLUC

Gene Name

Glucosylceramidase beta

Gene ID

2629

UniProt

P04062

Conjugation

Unconjugated

Related Pathways

Lysosome, Metabolic pathways, Other glycan degradation, Sphingolipid metabolism

Field of Research

Lysosome, Metabolic pathways, Other glycan degradation, Sphingolipid metabolism

Concentration

1 mg/ml

Dilution

WB 1:500, IHC 1:150

Form

PBS (PH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide.

Buffer

PBS (PH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide.

Function

Druggable Genome

Storage Conditions

Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.