RIP3 (RIPK3) Mouse Monoclonal Antibody [Clone ID: LBI3A3]

Product Specifications

Background

The product of this gene is a member of the receptor-interacting protein (RIP) family of serine/threonine protein kinases, and contains a C-terminal domain unique from other RIP family members. The encoded protein is predominantly localized to the cytoplasm, and can undergo nucleocytoplasmic shuttling dependent on novel nuclear localization and export signals. It is a component of the tumor necrosis factor (TNF) receptor-I signaling complex, and can induce apoptosis and weakly activate the NF-kappaB transcription factor. [provided by RefSeq, Jul 2008]

Overview

RIPK3 mouse monoclonal antibody, clone LBI3A3

Synonyms

RIP3

Gene Name

Receptor interacting serine/threonine kinase 3

Gene ID

11035

UniProt

Q9Y572

Conjugation

Unconjugated

Related Pathways

Cytosolic DNA-sensing pathway

Field of Research

Cytosolic DNA-sensing pathway

Concentration

1 mg/ml

Dilution

WB 1:200 - 1:1000, IHC 1:150

Form

PBS (PH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide.

Buffer

PBS (PH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide.

Function

Druggable Genome, Protein Kinase

Storage Conditions

Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.