PDE1A Mouse Monoclonal Antibody [Clone ID: LBI5C9]
Product Specifications
Background
Cyclic nucleotide phosphodiesterases (PDEs) play a role in signal transduction by regulating intracellular cyclic nucleotide concentrations through hydrolysis of cAMP and/or cGMP to their respective nucleoside 5-prime monophosphates. Members of the PDE1 family, such as PDE1A, are Ca (2+) /calmodulin (see CALM1; MIM 114180) -dependent PDEs (CaM-PDEs) that are activated by calmodulin in the presence of Ca (2+) (Michibata et al., 2001 [PubMed 11342109]; Fidock et al., 2002 [PubMed 11747989]) . [supplied by OMIM, Oct 2009]
Synonyms
CAM-PDE-1A; HCAM-1; HCAM1; HSPDE1A
Gene Name
Phosphodiesterase 1A
Gene ID
5136
UniProt
P54750
Conjugation
Unconjugated
Related Pathways
Calcium signaling pathway, Progesterone-mediated oocyte maturation, Purine metabolism, Taste transduction
Field of Research
Calcium signaling pathway, Progesterone-mediated oocyte maturation, Purine metabolism, Taste transduction
Concentration
1 mg/ml
Dilution
WB 1:2000
Form
PBS (PH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide.
Buffer
PBS (PH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide.
Function
Druggable Genome
Storage Conditions
Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.
Symbol
PDE1A
Overview
PDE1A mouse monoclonal antibody, clone LBI5C9
Gene ID URL
https://www.ncbi.nlm.nih.gov/gene/?term=5136
Uniprot URL
https://www.uniprot.org/uniprot/P54750
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