PDE1A Mouse Monoclonal Antibody [Clone ID: LBI5C9]

Product Specifications

Background

Cyclic nucleotide phosphodiesterases (PDEs) play a role in signal transduction by regulating intracellular cyclic nucleotide concentrations through hydrolysis of cAMP and/or cGMP to their respective nucleoside 5-prime monophosphates. Members of the PDE1 family, such as PDE1A, are Ca (2+) /calmodulin (see CALM1; MIM 114180) -dependent PDEs (CaM-PDEs) that are activated by calmodulin in the presence of Ca (2+) (Michibata et al., 2001 [PubMed 11342109]; Fidock et al., 2002 [PubMed 11747989]) . [supplied by OMIM, Oct 2009]

Overview

PDE1A mouse monoclonal antibody, clone LBI5C9

Synonyms

CAM-PDE-1A; HCAM-1; HCAM1; HSPDE1A

Gene Name

Phosphodiesterase 1A

Gene ID

5136

UniProt

P54750

Conjugation

Unconjugated

Related Pathways

Calcium signaling pathway, Progesterone-mediated oocyte maturation, Purine metabolism, Taste transduction

Field of Research

Calcium signaling pathway, Progesterone-mediated oocyte maturation, Purine metabolism, Taste transduction

Concentration

1 mg/ml

Dilution

WB 1:2000

Form

PBS (PH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide.

Buffer

PBS (PH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide.

Function

Druggable Genome

Storage Conditions

Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.