RIP3 (RIPK3) Mouse Monoclonal Antibody [Clone ID: LBI1B3]
Product Specifications
Background
The product of this gene is a member of the receptor-interacting protein (RIP) family of serine/threonine protein kinases, and contains a C-terminal domain unique from other RIP family members. The encoded protein is predominantly localized to the cytoplasm, and can undergo nucleocytoplasmic shuttling dependent on novel nuclear localization and export signals. It is a component of the tumor necrosis factor (TNF) receptor-I signaling complex, and can induce apoptosis and weakly activate the NF-kappaB transcription factor. [provided by RefSeq, Jul 2008]
Synonyms
RIP3
Gene Name
Receptor interacting serine/threonine kinase 3
Gene ID
11035
UniProt
Q9Y572
Conjugation
Unconjugated
Related Pathways
Cytosolic DNA-sensing pathway
Field of Research
Cytosolic DNA-sensing pathway
Concentration
1 mg/ml
Dilution
WB 1:200 - 1:1000, IHC 1:150
Form
PBS (PH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide.
Buffer
PBS (PH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide.
Function
Druggable Genome, Protein Kinase
Storage Conditions
Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.
Symbol
RIPK3
Overview
RIPK3 mouse monoclonal antibody, clone LBI1B3
Gene ID URL
https://www.ncbi.nlm.nih.gov/gene/?term=11035
Uniprot URL
https://www.uniprot.org/uniprot/Q9Y572
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