OAS2 Mouse Monoclonal Antibody [Clone ID: LBI3C1]
Product Specifications
Background
This gene encodes a member of the 2-5A synthetase family, essential proteins involved in the innate immune response to viral infection. The encoded protein is induced by interferons and uses adenosine triphosphate in 2'-specific nucleotidyl transfer reactions to synthesize 2',5'-oligoadenylates (2-5As) . These molecules activate latent RNase L, which results in viral RNA degradation and the inhibition of viral replication. The three known members of this gene family are located in a cluster on chromosome 12. Alternatively spliced transcript variants encoding different isoforms have been described. [provided by RefSeq, Jul
Synonyms
MGC78578
Gene Name
2'-5'-oligoadenylate synthetase 2
Gene ID
4939
UniProt
P29728
Conjugation
Unconjugated
Concentration
1 mg/ml
Dilution
WB 1:2000
Form
PBS (PH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide.
Buffer
PBS (PH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide.
Function
Druggable Genome
Storage Conditions
Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.
Symbol
OAS2
Overview
OAS2 mouse monoclonal antibody, clone LBI3C1
Gene ID URL
https://www.ncbi.nlm.nih.gov/gene/?term=4939
Uniprot URL
https://www.uniprot.org/uniprot/P29728
Curated Selection
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