VEGF Receptor 2 (KDR) Mouse Monoclonal Antibody [Clone ID: LBI2A1]
Product Specifications
Background
Vascular endothelial growth factor (VEGF) is a major growth factor for endothelial cells. This gene encodes one of the two receptors of the VEGF. This receptor, known as kinase insert domain receptor, is a type III receptor tyrosine kinase. It functions as the main mediator of VEGF-induced endothelial proliferation, survival, migration, tubular morphogenesis and sprouting. The signalling and trafficking of this receptor are regulated by multiple factors, including Rab GTPase, P2Y purine nucleotide receptor, integrin alphaVbeta3, T-cell protein tyrosine phosphatase, etc.. Mutations of this gene are implicated in infantile capillary hemangiomas. [provided by RefSeq, May 2009]
Synonyms
CD309; FLK1; VEGFR; VEGFR2
Gene Name
Kinase insert domain receptor
Gene ID
3791
UniProt
P35968
Conjugation
Unconjugated
Related Pathways
Cytokine-cytokine receptor interaction, Endocytosis, Focal adhesion, VEGF signaling pathway
Field of Research
Cytokine-cytokine receptor interaction, Endocytosis, Focal adhesion, VEGF signaling pathway
Concentration
1 mg/ml
Dilution
WB 1:2000
Form
PBS (PH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide.
Buffer
PBS (PH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide.
Function
Druggable Genome, ES Cell Differentiation/IPS, Protein Kinase, Transmembrane
Storage Conditions
Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.
Symbol
KDR
Overview
KDR mouse monoclonal antibody, clone LBI2A1
Gene ID URL
https://www.ncbi.nlm.nih.gov/gene/?term=3791
Uniprot URL
https://www.uniprot.org/uniprot/P35968
Curated Selection
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