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NUMB Mouse Monoclonal Antibody [Clone ID: LBI2E8]

Product Specifications

Background

The protein encoded by this gene plays a role in the determination of cell fates during development. The encoded protein, whose degradation is induced in a proteasome-dependent manner by MDM2, is a membrane-bound protein that has been shown to associate with EPS15, LNX1, and NOTCH1. Four transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008]

Synonyms

C14orf41; c14_5527; S171

Gene Name

NUMB, endocytic adaptor protein

Gene ID

8650

UniProt

P49757

Conjugation

Unconjugated

Related Pathways

Notch signaling pathway

Field of Research

Notch signaling pathway

Concentration

1 mg/ml

Dilution

WB 1:2000

Form

PBS (PH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide.

Buffer

PBS (PH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide.

Storage Conditions

Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.

Symbol

NUMB

Overview

NUMB mouse monoclonal antibody, clone LBI2E8

Gene ID URL

https://www.ncbi.nlm.nih.gov/gene/?term=8650

Uniprot URL

https://www.uniprot.org/uniprot/P49757

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