CD137 (TNFRSF9) Mouse Monoclonal Antibody [Clone ID: LBI7F9]

Product Specifications

Background

The protein encoded by this gene is a member of the TNF-receptor superfamily. This receptor contributes to the clonal expansion, survival, and development of T cells. It can also induce proliferation in peripheral monocytes, enhance T cell apoptosis induced by TCR/CD3 triggered activation, and regulate CD28 co-stimulation to promote Th1 cell responses. The expression of this receptor is induced by lymphocyte activation. TRAF adaptor proteins have been shown to bind to this receptor and transduce the signals leading to activation of NF-kappaB. [provided by RefSeq, Jul 2008]

Overview

TNFRSF9 mouse monoclonal antibody, clone LBI7F9

Synonyms

4-1BB; CD137; CDw137; ILA

Gene Name

Tumor necrosis factor receptor superfamily member 9

Gene ID

3604

UniProt

Q07011

Conjugation

Unconjugated

Related Pathways

Cytokine-cytokine receptor interaction

Field of Research

Cytokine-cytokine receptor interaction

Concentration

1 mg/ml

Dilution

WB 1:2000

Form

PBS (PH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide.

Buffer

PBS (PH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide.

Function

Druggable Genome, Transmembrane

Storage Conditions

Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.