CD137 (TNFRSF9) Mouse Monoclonal Antibody [Clone ID: LBI5H5]
Product Specifications
Background
The protein encoded by this gene is a member of the TNF-receptor superfamily. This receptor contributes to the clonal expansion, survival, and development of T cells. It can also induce proliferation in peripheral monocytes, enhance T cell apoptosis induced by TCR/CD3 triggered activation, and regulate CD28 co-stimulation to promote Th1 cell responses. The expression of this receptor is induced by lymphocyte activation. TRAF adaptor proteins have been shown to bind to this receptor and transduce the signals leading to activation of NF-kappaB. [provided by RefSeq, Jul 2008]
Overview
TNFRSF9 mouse monoclonal antibody, clone LBI5H5
Synonyms
4-1BB; CD137; CDw137; ILA
Gene Name
Tumor necrosis factor receptor superfamily member 9
Gene ID
3604
UniProt
Q07011
Conjugation
Unconjugated
Related Pathways
Cytokine-cytokine receptor interaction
Field of Research
Cytokine-cytokine receptor interaction
Concentration
1 mg/ml
Dilution
WB 1:2000
Form
PBS (PH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide.
Buffer
PBS (PH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide.
Function
Druggable Genome, Transmembrane
Storage Conditions
Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.
Symbol
TNFRSF9
Gene ID URL
https://www.ncbi.nlm.nih.gov/gene/?term=3604
Uniprot URL
https://www.uniprot.org/uniprot/Q07011
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