Neuraminidase (NEU1) Mouse Monoclonal Antibody [Clone ID: LBI3C5]
Product Specifications
Background
The protein encoded by this gene is a lysosomal enzyme that cleaves terminal sialic acid residues from substrates such as glycoproteins and glycolipids. In the lysosome, this enzyme is part of a heterotrimeric complex together with beta-galactosidase and cathepsin A (the latter is also referred to as 'protective protein') . Mutations in this gene can lead to sialidosis, a lysosomal storage disease that can be type 1 (cherry red spot-myoclonus syndrome or normosomatic type), which is late-onset, or type 2 (the dysmorphic type), which occurs at an earlier age with increased severity. [provided by RefSeq, Jul 2008]
Synonyms
NANH; NEU; SIAL1
Gene Name
Neuraminidase 1 (lysosomal sialidase)
Gene ID
4758
UniProt
Q99519
Conjugation
Unconjugated
Related Pathways
Lysosome, Other glycan degradation, Sphingolipid metabolism
Field of Research
Lysosome, Other glycan degradation, Sphingolipid metabolism
Concentration
1 mg/ml
Dilution
WB 1:2000
Form
PBS (PH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide.
Buffer
PBS (PH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide.
Function
Druggable Genome, Transmembrane
Storage Conditions
Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.
Symbol
NEU1
Overview
NEU1 mouse monoclonal antibody, clone LBI3C5
Gene ID URL
https://www.ncbi.nlm.nih.gov/gene/?term=4758
Uniprot URL
https://www.uniprot.org/uniprot/Q99519
Curated Selection
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