NM23A (NME1) Mouse Monoclonal Antibody [Clone ID: LBI7E5]

Product Specifications

Background

This gene (NME1) was identified because of its reduced mRNA transcript levels in highly metastatic cells. Nucleoside diphosphate kinase (NDK) exists as a hexamer composed of 'A' (encoded by this gene) and 'B' (encoded by NME2) isoforms. Mutations in this gene have been identified in aggressive neuroblastomas. Two transcript variants encoding different isoforms have been found for this gene. Co-transcription of this gene and the neighboring downstream gene (NME2) generates naturally-occurring transcripts (NME1-NME2), which encodes a fusion protein comprised of sequence sharing identity with each individual gene product. [provided by RefSeq, Jul 2008]

Overview

NME1 mouse monoclonal antibody, clone LBI7E5

Synonyms

AWD; GAAD; NB; NBS; NDKA; NDPK-A; NDPKA; NM23; NM23-H1

Gene Name

NME/NM23 nucleoside diphosphate kinase 1

Gene ID

4830

UniProt

P15531

Conjugation

Unconjugated

Related Pathways

Metabolic pathways, Purine metabolism, Pyrimidine metabolism

Field of Research

Metabolic pathways, Purine metabolism, Pyrimidine metabolism

Concentration

1 mg/ml

Dilution

WB 1:2000, IHC 1:50~150

Form

PBS (PH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide.

Buffer

PBS (PH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide.

Function

Druggable Genome, Stem cell - Pluripotency

Storage Conditions

Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.