P95 NBS1 (NBN) Mouse Monoclonal Antibody [Clone ID: LBI5A6]

Product Specifications

Background

Mutations in this gene are associated with Nijmegen breakage syndrome, an autosomal recessive chromosomal instability syndrome characterized by microcephaly, growth retardation, immunodeficiency, and cancer predisposition. The encoded protein is a member of the MRE11/RAD50 double-strand break repair complex which consists of 5 proteins. This gene product is thought to be involved in DNA double-strand break repair and DNA damage-induced checkpoint activation. [provided by RefSeq, Jul 2008]

Overview

NBN (p95 NBS1) mouse monoclonal antibody, clone LBI5A6

Synonyms

AT-V1; AT-V2; ATV; NBS; NBS1; P95

Gene Name

Nibrin

Gene ID

4683

UniProt

O60934

Conjugation

Unconjugated

Related Pathways

Homologous recombination

Field of Research

Homologous recombination

Concentration

1 mg/ml

Dilution

WB 1:2000

Form

PBS (PH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide.

Buffer

PBS (PH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide.

Function

Druggable Genome

Storage Conditions

Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.