NFH (NEFH) Mouse Monoclonal Antibody [Clone ID: LBI10A7]
Product Specifications
Background
Neurofilaments are type IV intermediate filament heteropolymers composed of light, medium, and heavy chains. Neurofilaments comprise the axoskeleton and functionally maintain neuronal caliber. They may also play a role in intracellular transport to axons and dendrites. This gene encodes the heavy neurofilament protein. This protein is commonly used as a biomarker of neuronal damage and susceptibility to amyotrophic lateral sclerosis (ALS) has been associated with mutations in this gene. [provided by RefSeq, Oct 2008]
Synonyms
CMT2CC; NFH
Gene Name
Neurofilament, heavy polypeptide
Gene ID
4744
UniProt
P12036
Conjugation
Unconjugated
Related Pathways
Amyotrophic lateral sclerosis (ALS)
Field of Research
Amyotrophic lateral sclerosis (ALS)
Concentration
1 mg/ml
Dilution
WB 1:2000, IHC 1:2000
Form
PBS (PH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide.
Buffer
PBS (PH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide.
Function
Druggable Genome
Storage Conditions
Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.
Symbol
NEFH
Overview
NEFH mouse monoclonal antibody, clone LBI10A7
Gene ID URL
https://www.ncbi.nlm.nih.gov/gene/?term=4744
Uniprot URL
https://www.uniprot.org/uniprot/P12036
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