NFH (NEFH) Mouse Monoclonal Antibody [Clone ID: LBI10A7]

Product Specifications

Background

Neurofilaments are type IV intermediate filament heteropolymers composed of light, medium, and heavy chains. Neurofilaments comprise the axoskeleton and functionally maintain neuronal caliber. They may also play a role in intracellular transport to axons and dendrites. This gene encodes the heavy neurofilament protein. This protein is commonly used as a biomarker of neuronal damage and susceptibility to amyotrophic lateral sclerosis (ALS) has been associated with mutations in this gene. [provided by RefSeq, Oct 2008]

Overview

NEFH mouse monoclonal antibody, clone LBI10A7

Synonyms

CMT2CC; NFH

Gene Name

Neurofilament, heavy polypeptide

Gene ID

4744

UniProt

P12036

Conjugation

Unconjugated

Related Pathways

Amyotrophic lateral sclerosis (ALS)

Field of Research

Amyotrophic lateral sclerosis (ALS)

Concentration

1 mg/ml

Dilution

WB 1:2000, IHC 1:2000

Form

PBS (PH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide.

Buffer

PBS (PH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide.

Function

Druggable Genome

Storage Conditions

Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.