Estrogen Receptor beta (ESR2) Mouse Monoclonal Antibody [Clone ID: LBI2E12]

Product Specifications

Background

This gene encodes a member of the family of estrogen receptors and superfamily of nuclear receptor transcription factors. The gene product contains an N-terminal DNA binding domain and C-terminal ligand binding domain and is localized to the nucleus, cytoplasm, and mitochondria. Upon binding to 17beta-estradiol or related ligands, the encoded protein forms homo- or hetero-dimers that interact with specific DNA sequences to activate transcription. Some isoforms dominantly inhibit the activity of other estrogen receptor family members. Several alternatively spliced transcript variants of this gene have been described, but the full-length nature of some of these variants has not been fully characterized. [provided by RefSeq, Jul 2008]

Overview

ESR2 mouse monoclonal antibody, clone LBI2E12

Synonyms

ER-BETA; Erb; ESR-BETA; ESRB; ESTRB; NR3A2

Gene Name

Estrogen receptor 2

Gene ID

2100

UniProt

Q92731

Conjugation

Unconjugated

Concentration

1 mg/ml

Dilution

WB 1:500~2000

Form

PBS (PH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide.

Buffer

PBS (PH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide.

Function

Druggable Genome, Nuclear Hormone Receptor, Transcription Factors

Storage Conditions

Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.