TRIF (TICAM1) Mouse Monoclonal Antibody [Clone ID: LBI1G7]

Product Specifications

Background

This gene encodes an adaptor protein containing a Toll/interleukin-1 receptor (TIR) homology domain, which is an intracellular signaling domain that mediates protein-protein interactions between the Toll-like receptors (TLRs) and signal-transduction components. This protein is involved in native immunity against invading pathogens. It specifically interacts with toll-like receptor 3, but not with other TLRs, and this association mediates dsRNA induction of interferon-beta through activation of nuclear factor kappa-B, during an antiviral immune response. [provided by RefSeq, Jan 2012]

Overview

TICAM1 (TRIF) mouse monoclonal antibody, clone LBI1G7

Synonyms

IIAE6; MyD88-3; PRVTIRB; TICAM-1; TRIF

Gene Name

Toll like receptor adaptor molecule 1

Gene ID

148022

UniProt

Q8IUC6

Conjugation

Unconjugated

Related Pathways

Toll-like receptor signaling pathway

Field of Research

Toll-like receptor signaling pathway

Concentration

1 mg/ml

Dilution

WB 1:2000

Form

PBS (PH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide.

Buffer

PBS (PH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide.

Function

Druggable Genome

Storage Conditions

Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.