HSD17B8 Mouse Monoclonal Antibody [Clone ID: LBI6H2]
Product Specifications
Background
In mice, the Ke6 protein is a 17-beta-hydroxysteroid dehydrogenase that can regulate the concentration of biologically active estrogens and androgens. It is preferentially an oxidative enzyme and inactivates estradiol, testosterone, and dihydrotestosterone. However, the enzyme has some reductive activity and can synthesize estradiol from estrone. The protein encoded by this gene is similar to Ke6 and is a member of the short-chain dehydrogenase superfamily. An alternatively spliced transcript of this gene has been detected, but the full-length nature of this variant has not been determined. [provided by RefSeq, Jul 2008]
Synonyms
D6S2245E; dJ1033B10.9; FABG; FABGL; H2-KE6; HKE6; KE6; RING2; SDR30C1
Gene Name
Hydroxysteroid (17-beta) dehydrogenase 8
Gene ID
7923
UniProt
Q92506
Conjugation
Unconjugated
Related Pathways
Androgen and estrogen metabolism, Metabolic pathways
Field of Research
Androgen and estrogen metabolism, Metabolic pathways
Concentration
1 mg/ml
Dilution
WB 1:2000, IHC 1:150
Form
PBS (PH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide.
Buffer
PBS (PH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide.
Function
Druggable Genome
Storage Conditions
Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.
Symbol
HSD17B8
Overview
HSD17B8 mouse monoclonal antibody, clone LBI6H2
Gene ID URL
https://www.ncbi.nlm.nih.gov/gene/?term=7923
Uniprot URL
https://www.uniprot.org/uniprot/Q92506
Curated Selection
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