Methionine Aminopeptidase 2 (METAP2) Mouse Monoclonal Antibody [Clone ID: LBI1F6]
Product Specifications
Background
This gene is a member of the methionyl aminopeptidase family and encodes a protein that binds 2 cobalt or manganese ions. This protein functions both by protecting the alpha subunit of eukaryotic initiation factor 2 from inhibitory phosphorylation and by removing the amino-terminal methionine residue from nascent protein. Increased expression of this gene is associated with various forms of cancer and the anti-cancer drugs fumagillin and ovalicin inhibit the protein by irreversibly binding to its active site. A pseudogene of this gene is located on chromosome 2. [provided by RefSeq]
Synonyms
MAP2; MNPEP; p67eIF2
Gene Name
Methionyl aminopeptidase 2
Gene ID
10988
UniProt
P50579
Conjugation
Unconjugated
Concentration
1 mg/ml
Dilution
WB 1:2000, IHC 1:150, IF 1:100, FLOW 1:100
Form
PBS (PH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide.
Buffer
PBS (PH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide.
Function
Druggable Genome, Protease
Storage Conditions
Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.
Symbol
METAP2
Overview
METAP2 (Methionine Aminopeptidase 2) mouse monoclonal antibody, clone LBI1F6
Gene ID URL
https://www.ncbi.nlm.nih.gov/gene/?term=10988
Uniprot URL
https://www.uniprot.org/uniprot/P50579
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