RFC2 Mouse Monoclonal Antibody [Clone ID: LBI5A1]
Product Specifications
Background
The elongation of primed DNA templates by DNA polymerase delta and epsilon requires the action of the accessory proteins, proliferating cell nuclear antigen (PCNA) and replication factor C (RFC) . RFC, also called activator 1, is a protein complex consisting of five distinct subunits of 145, 40, 38, 37, and 36.5 kD. This gene encodes the 40 kD subunit, which has been shown to be responsible for binding ATP. Deletion of this gene has been associated with Williams syndrome. Alternatively spliced transcript variants encoding distinct isoforms have been described. [provided by RefSeq]
Synonyms
RFC40
Gene Name
Replication factor C subunit 2
Gene ID
5982
UniProt
P35250
Conjugation
Unconjugated
Related Pathways
DNA replication, Mismatch repair, Nucleotide excision repair
Field of Research
DNA replication, Mismatch repair, Nucleotide excision repair
Concentration
1 mg/ml
Dilution
WB 1:2000, IHC 1:150, FLOW 1:100
Form
PBS (PH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide.
Buffer
PBS (PH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide.
Function
Druggable Genome, Stem cell - Pluripotency
Storage Conditions
Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.
Symbol
RFC2
Overview
RFC2 mouse monoclonal antibody, clone LBI5A1
Gene ID URL
https://www.ncbi.nlm.nih.gov/gene/?term=5982
Uniprot URL
https://www.uniprot.org/uniprot/P35250
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