RFC2 Mouse Monoclonal Antibody [Clone ID: LBI5A1]

Product Specifications

Background

The elongation of primed DNA templates by DNA polymerase delta and epsilon requires the action of the accessory proteins, proliferating cell nuclear antigen (PCNA) and replication factor C (RFC) . RFC, also called activator 1, is a protein complex consisting of five distinct subunits of 145, 40, 38, 37, and 36.5 kD. This gene encodes the 40 kD subunit, which has been shown to be responsible for binding ATP. Deletion of this gene has been associated with Williams syndrome. Alternatively spliced transcript variants encoding distinct isoforms have been described. [provided by RefSeq]

Overview

RFC2 mouse monoclonal antibody, clone LBI5A1

Synonyms

RFC40

Gene Name

Replication factor C subunit 2

Gene ID

5982

UniProt

P35250

Conjugation

Unconjugated

Related Pathways

DNA replication, Mismatch repair, Nucleotide excision repair

Field of Research

DNA replication, Mismatch repair, Nucleotide excision repair

Concentration

1 mg/ml

Dilution

WB 1:2000, IHC 1:150, FLOW 1:100

Form

PBS (PH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide.

Buffer

PBS (PH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide.

Function

Druggable Genome, Stem cell - Pluripotency

Storage Conditions

Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.