SnoN (SKIL) Mouse Monoclonal Antibody [Clone ID: LBI2F6]

Product Specifications

Background

The protein encoded by this gene is a component of the SMAD pathway, which regulates cell growth and differentiation through transforming growth factor-beta (TGFB) . In the absence of ligand, the encoded protein binds to the promoter region of TGFB-responsive genes and recruits a nuclear repressor complex. TGFB signaling causes SMAD3 to enter the nucleus and degrade this protein, allowing these genes to be activated. Four transcript variants encoding three different isoforms have been found for this gene. [provided by RefSeq, Oct 2011]

Overview

SKIL (SnoN) mouse monoclonal antibody, clone LBI2F6

Synonyms

SNO; SnoA; SnoI; SnoN

Gene Name

SKI-like proto-oncogene

Gene ID

6498

UniProt

P12757

Conjugation

Unconjugated

Concentration

1 mg/ml

Dilution

WB 1:500~2000, IHC 1:150

Form

PBS (PH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide.

Buffer

PBS (PH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide.

Function

Druggable Genome, Transcription Factors

Storage Conditions

Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.