DHLAG (CD74) Mouse Monoclonal Antibody [Clone ID: LBI1H3]
Product Specifications
Background
The protein encoded by this gene associates with class II major histocompatibility complex (MHC) and is an important chaperone that regulates antigen presentation for immune response. It also serves as cell surface receptor for the cytokine macrophage migration inhibitory factor (MIF) which, when bound to the encoded protein, initiates survival pathways and cell proliferation. This protein also interacts with amyloid precursor protein (APP) and suppresses the production of amyloid beta (Abeta) . Multiple alternatively spliced transcript variants encoding different isoforms have been identified. [provided by RefSeq, Aug 2011]
Synonyms
DHLAG; HLADG; Ia-GAMMA; II
Gene Name
CD74 molecule
Gene ID
972
UniProt
P04233
Conjugation
Unconjugated
Related Pathways
Antigen processing and presentation
Field of Research
Antigen processing and presentation
Concentration
1 mg/ml
Dilution
WB 1:4000, IHC 1:150
Form
PBS (PH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide.
Buffer
PBS (PH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide.
Function
Druggable Genome, Transmembrane
Storage Conditions
Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.
Symbol
CD74
Overview
CD74 mouse monoclonal antibody, clone LBI1H3
Gene ID URL
https://www.ncbi.nlm.nih.gov/gene/?term=972
Uniprot URL
https://www.uniprot.org/uniprot/P04233
Curated Selection
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