BRD4-IN-5
BRD4-IN-5 (example 51) is a BRD4 inhibitor. The Ki values of the two BRD4 domains BDI_K57-E168 and BDII_E352-M457 are 9.7 nM and 16.1 nM, respectively. BRD4-IN-5 can be used in cancer research[1].
Product Specifications
CAS Number
1445993-41-8
UNSPSC
12352005
Target
Epigenetic Reader Domain
Type
Reference compound
Related Pathways
Epigenetics
Applications
Cancer-programmed cell death
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/brd4-in-5.html
Solubility
10 mM in DMSO
Smiles
CN1C=C(C2=C(OC3=C(F)C=C(F)C=C3)C=CC(C(NC4CCOC4)=O)=C2)C5=C(NC=C5)C1=O
Molecular Formula
C25H21F2N3O4
Molecular Weight
465.45
References & Citations
[1]Le Wang, et al. Bromodomain inhibitors. International Publication Date. 2013.04.07.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Isoform
BRD4
Frequently Asked Questions
More Discoveries
Explore Other Products
Browse additional items from our catalog
MBS6216260-01 0.1 mL
CDH2 (Cadherin 2, Type 1, N-Cadherin (Neuronal), CD325, CDHN, CDw325, NCAD) (MaxLight 550)
Sign In for Pricing
View Details MBS6216260-02 5x 0.1 mL
CDH2 (Cadherin 2, Type 1, N-Cadherin (Neuronal), CD325, CDHN, CDw325, NCAD) (MaxLight 550)
Sign In for Pricing
View Details 
HY-30440-01 100 mg
(S) -1- (4- (Trifluoromethoxy) phenyl) ethanamine
Sign In for Pricing
View Details HY-30440-02 250 mg
(S) -1- (4- (Trifluoromethoxy) phenyl) ethanamine
Sign In for Pricing
View Details