Fibrinogen gamma chain (FGG) Mouse Monoclonal Antibody [Clone ID: LBI2D2]
Product Specifications
Background
The protein encoded by this gene is the gamma component of fibrinogen, a blood-borne glycoprotein comprised of three pairs of nonidentical polypeptide chains. Following vascular injury, fibrinogen is cleaved by thrombin to form fibrin which is the most abundant component of blood clots. In addition, various cleavage products of fibrinogen and fibrin regulate cell adhesion and spreading, display vasoconstrictor and chemotactic activities, and are mitogens for several cell types. Mutations in this gene lead to several disorders, including dysfibrinogenemia, hypofibrinogenemia and thrombophilia. Alternative splicing results in two transcript variants encoding different isoforms. [provided by RefSeq, Jul
Synonyms
Fibrinogen; fibrinogen gamma chain; gamma chain; gamma polypeptide
Gene Name
Fibrinogen gamma chain
Gene ID
2266
UniProt
P02679
Conjugation
Unconjugated
Related Pathways
Complement and coagulation cascades
Field of Research
Complement and coagulation cascades
Concentration
1 mg/ml
Dilution
WB 1:400~4000, IHC 1:150
Form
PBS (PH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide.
Buffer
PBS (PH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide.
Function
Druggable Genome, Secreted Protein, Transmembrane
Storage Conditions
Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.
Symbol
FGG
Overview
FGG mouse monoclonal antibody, clone LBI2D2
Gene ID URL
https://www.ncbi.nlm.nih.gov/gene/?term=2266
Uniprot URL
https://www.uniprot.org/uniprot/P02679
Curated Selection
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