Claudin 6 (CLDN6) Mouse Monoclonal Antibody [Clone ID: LBI2A3]
Product Specifications
Background
Tight junctions represent one mode of cell-to-cell adhesion in epithelial or endothelial cell sheets, forming continuous seals around cells and serving as a physical barrier to prevent solutes and water from passing freely through the paracellular space. These junctions are comprised of sets of continuous networking strands in the outwardly facing cytoplasmic leaflet, with complementary grooves in the inwardly facing extracytoplasmic leaflet. This gene encodes a component of tight junction strands, which is a member of the claudin family. The protein is an integral membrane protein and is one of the entry cofactors for hepatitis C virus. The gene methylation may be involved in esophageal tumorigenesis. This gene is adjacent to another family member CLDN9 on chromosome 16. [provided by RefSeq, Aug 2010]
Synonyms
Claudin 6; OTTHUMP00000159248
Gene Name
Claudin 6
Gene ID
9074
UniProt
P56747
Conjugation
Unconjugated
Related Pathways
Cell adhesion molecules (CAMs), Leukocyte transendothelial migration, Tight junction
Field of Research
Cell adhesion molecules (CAMs), Leukocyte transendothelial migration, Tight junction
Concentration
1 mg/ml
Dilution
WB 1:500
Form
PBS (PH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide.
Buffer
PBS (PH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide.
Function
Transmembrane
Storage Conditions
Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.
Symbol
CLDN6
Overview
CLDN6 mouse monoclonal antibody, clone LBI2A3
Gene ID URL
https://www.ncbi.nlm.nih.gov/gene/?term=9074
Uniprot URL
https://www.uniprot.org/uniprot/P56747
Curated Selection
Explore Other Products
Discover premium biology products from our extensive collection of 20M+ items
