GRF2 (RAPGEF1) Mouse Monoclonal Antibody [Clone ID: LBI2B5]

Product Specifications

Background

This gene encodes a human guanine nucleotide exchange factor. It transduces signals from CRK by binding the SH3 domain of CRK, and activating several members of the Ras family of GTPases. This signaling cascade that may be involved in apoptosis, integrin-mediated signal transduction, and cell transformation. Several alternatively spliced transcript variants of this gene have been described, but the full-length nature of some variants has not been determined. [provided by RefSeq, Jul 2008]

Overview

RAPGEF1 mouse monoclonal antibody, clone LBI2B5

Synonyms

C3G; GRF2

Gene Name

Rap guanine nucleotide exchange factor 1

Gene ID

2889

UniProt

Q13905

Conjugation

Unconjugated

Related Pathways

Focal adhesion, Insulin signaling pathway, Neurotrophin signaling pathway, Renal cell carcinoma

Field of Research

Focal adhesion, Insulin signaling pathway, Neurotrophin signaling pathway, Renal cell carcinoma

Concentration

1 mg/ml

Dilution

WB 1:4000, IHC: 1:150

Form

PBS (PH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide.

Buffer

PBS (PH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide.

Function

Druggable Genome

Storage Conditions

Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.