Oct4 (POU5F1) Mouse Monoclonal Antibody [Clone ID: LBI7H1]
Product Specifications
Background
This gene encodes a transcription factor containing a POU homeodomain. This transcription factor plays a role in embryonic development, especially during early embryogenesis, and it is necessary for embryonic stem cell pluripotency. A translocation of this gene with the Ewing's sarcoma gene, t (6;22) (p21; q12), has been linked to tumor formation. Alternative splicing, as well as usage of alternative translation initiation codons, results in multiple isoforms, one of which initiates at a non-AUG (CUG) start codon. Related pseudogenes have been identified on chromosomes 1, 3, 8, 10, and 12. [provided by RefSeq, Mar 2010]
Synonyms
Oct-3; Oct-4; OCT3; OCT4; OTF-3; OTF3; OTF4
Gene Name
POU class 5 homeobox 1
Gene ID
5460
UniProt
Q01860
Conjugation
Unconjugated
Concentration
1 mg/ml
Dilution
WB 1:200~1000, IF: 1:100
Form
PBS (PH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide.
Buffer
PBS (PH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide.
Function
Adult stem cells, Cancer stem cells, Embryonic stem cells, Induced pluripotent stem cells, Stem cell - Pluripotency, Transcription Factors
Storage Conditions
Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.
Symbol
POU5F1
Overview
POU5F1 mouse monoclonal antibody, clone LBI7H1
Gene ID URL
https://www.ncbi.nlm.nih.gov/gene/?term=5460
Uniprot URL
https://www.uniprot.org/uniprot/Q01860
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