BID Mouse Monoclonal Antibody [Clone ID: LBI3C8]
Product Specifications
Background
This gene encodes a death agonist that heterodimerizes with either agonist BAX or antagonist BCL2. The encoded protein is a member of the BCL-2 family of cell death regulators. It is a mediator of mitochondrial damage induced by caspase-8 (CASP8) ; CASP8 cleaves this encoded protein, and the COOH-terminal part translocates to mitochondria where it triggers cytochrome c release. Multiple alternatively spliced transcript variants have been found, but the full-length nature of some variants has not been defined. [provided by RefSeq, Jul 2008]
Synonyms
FP497
Gene Name
BH3 interacting domain death agonist
Gene ID
637
UniProt
P55957
Conjugation
Unconjugated
Related Pathways
Alzheimer's disease, Amyotrophic lateral sclerosis (ALS), Apoptosis, Natural killer cell mediated cytotoxicity, p53 signaling pathway, Pathways in cancer, Viral myocarditis
Field of Research
Alzheimer's disease, Amyotrophic lateral sclerosis (ALS), Apoptosis, Natural killer cell mediated cytotoxicity, p53 signaling pathway, Pathways in cancer, Viral myocarditis
Concentration
1 mg/ml
Dilution
WB 1:400~4000, IHC 1:150, IF 1:100
Form
PBS (PH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide.
Buffer
PBS (PH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide.
Function
Druggable Genome
Storage Conditions
Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.
Symbol
BID
Overview
BID mouse monoclonal antibody, clone LBI3C8
Gene ID URL
https://www.ncbi.nlm.nih.gov/gene/?term=637
Uniprot URL
https://www.uniprot.org/uniprot/P55957
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